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Posted: December 24th, 2022

BS7203 Liver case study

CLINICAL REPORT –
Module BS7203: Biology of Disease and Clinical Diagnosis Biomedical Science — Level 7

BS7203 Liver case study
The table below contains the clinical chemistry results from the plasma and urine of a patient with suspected liver disease. Answer the following questions (1-3) and submit them to the moodle site BS7203 under liver case study exercise.
Please remember to use your own words as turnitin will reveal if you have simply taken your answers from other students or from the internet.
Questions
1). Looking at the information provided in Table 1 below and your knowledge of liver function and dysfunction. (a) State if the patient has either; pre, intra or post hepatic disease or no disease and briefly explaining why. (b) Identify the most likely liver disease based on the information in the Table and the brief case history and suggest the likely cause of the liver disease. (40marks)
2). Use your knowledge of liver function and dysfunction to write a more comprehensive case history of the individual in this case. This case history will have a summary of what symptoms would have led the patient to visit the doctor and information about their background such as what could have caused the condition. (30 marks)
3). Complete the Table below by adding the actual reference values you would expect (values can be found on the internet or in clinical chemistry textbooks) for each parameter and then in the last column estimate the most likely patient plasma value including units for a patient in that situation, so for example if serum albumin is normal (N) then it should be 40-45g/L. (30marks)
Brief case history of the patient: An adolescent boy went to his doctor complaining of stress from exams and feeling slightly unwell but no other symptoms.
Table 1 Case 1
Case 1 Reference value Estimate of Patient Value
Haemoglobin N
Clotting time N
Albumin N
Urine Bilirubin N
Conjugated Bilirubin N
Total Bilirubin 
Urobilinogen 
AST N
ALP N

N= normal,  a slight but significant increase above upper limit of normal,  a large significant increase well above the upper limit of normal,  a very large and significant increase above the upper limit of normal.

TEST RESULT UNITS CONTROL VALUES
Bilirubin Total:
Direct:

ALP:
AST:

Student ID number:

TEST RESULT UNITS CONTROL VALUES
Bilirubin Total:
Direct:

ALP:
AST:

Student ID number:

TEST RESULT UNITS CONTROL VALUES
Bilirubin Total:
Direct:

ALP:
AST:

Student ID number:

TEST RESULT UNITS CONTROL VALUES
Bilirubin Total:
Direct:

ALP:
AST:

Student ID number:

Student ID number:

– Laboratory number: to each sample it is assigned a unique identification number (a label typically printed on the sample
container). Choose your own format and be consistent with it.
– Instrumentation used: type and model.
– If the sample is not conformed to the requirements, the analysis cannot be carried out and an additional patient sample
must be requested.
1
Reasons for referral (max 100 words):
Write here a short history of the patient based on the medical history you have been provided.
Usually, this section is present in the analysis request form, and it is written by the doctor requesting the test.
It contains all the information considered relevant to help with the diagnosis (e.g., symptoms, previous diseased etc.)
Conclusions (suggestion of additional diagnostic tests to confirm the diagnosis, if appropriate) (max 100 words).
Write in this section a short interpretation/comment of the analytical findings.
Please note here any variations from the SOP and any problems you had while following the SOP for the analysis of
the 4 samples (if applicable):
Fill this section ONLY if you encountered problems while following the SOP otherwise write N/A.

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