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Posted: December 20th, 2022

PHARMACOTHERAPY FOR GASTROINTESTINAL AND HEPATOBILIARY DISORDERS

To Prepare:
• Review the case study assigned by your Instructor for this Assignment
• Reflect on the patient’s symptoms, medical history, and drugs currently prescribed.
• Think about a possible diagnosis for the patient. Consider whether the patient has a disorder related to the gastrointestinal and hepatobiliary system or whether the symptoms are the result of a disorder from another system or other factors, such as pregnancy, drugs, or a psychological disorder.
• Consider an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.

Write a 1-page paper that addresses the following:
• Explain your diagnosis for the patient, including your rationale for the diagnosis.
• Describe an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.
• Justify why you would recommend this drug therapy plan for this patient. Be specific and provide examples.

Case Study:
DC is a 46-year-old female who presents with a 24-hour history of RUQ pain. She states the pain started about 1 hour after a large dinner she had with her family. She has had nausea and on instance of vomiting before presentation.
PMH: Vitals:
HTN Temp: 98.8oF
Type II DM Wt: 202 lbs
Gout Ht: 5’8”
DVT – Caused by oral BCPs BP: 136/82
HR: 82 bpm
Current Medications: Notable Labs:
Lisinopril 10 mg daily WBC: 13,000/mm3
HCTZ 25 mg daily Total bilirubin: 0.8 mg/dL
Allopurinol 100 mg daily Direct bilirubin: 0.6 mg/dL
Multivitamin daily Alk Phos: 100 U/L
AST: 45 U/L
ALT: 30 U/L
Allergies:
• Latex
• Codeine
• Amoxicillin
PE:
• Eyes: EOMI
• HENT: Normal
• GI:bNondistended, minimal tenderness
• Skin:bWarm and dry
• Neuro: Alert and Oriented
• Psych:bAppropriate mood

APA Format
min 2-3 resources

RUQ stands for right upper quadrant, which refers to the area of the abdomen on the right side, just below the rib cage. Pain in this area can be caused by a variety of conditions, including:

Gallstones: Small stones that form in the gallbladder can cause pain in the RUQ, especially after eating.
Acute pancreatitis: Inflammation of the pancreas can cause severe pain in the RUQ.
Hepatitis: Inflammation of the liver can cause pain in the RUQ.
Appendicitis: Inflammation of the appendix, a small organ located in the RUQ, can cause severe abdominal pain.
Cholecystitis: Inflammation of the gallbladder can cause RUQ pain.
If you are experiencing RUQ pain, it is important to see a healthcare professional for a proper diagnosis and treatment. The specific treatment will depend on the underlying cause of the pain.

Pharmacotherapy is the use of medications to treat and manage gastrointestinal (GI) and hepatobiliary disorders. These disorders include conditions such as acid reflux, inflammatory bowel disease, and liver disease.

There are many different medications that can be used to treat GI and hepatobiliary disorders. Some common medications include:

Antacids: These medications neutralize stomach acid and can be used to treat acid reflux and heartburn. Examples include magnesium hydroxide (Milk of Magnesia) and aluminum hydroxide (Maalox).

Proton pump inhibitors (PPIs): These medications reduce the production of stomach acid and are used to treat acid reflux and ulcers. Examples include omeprazole (Prilosec) and lansoprazole (Prevacid).

H2 receptor antagonists: These medications also reduce the production of stomach acid and are used to treat acid reflux and ulcers. Examples include ranitidine (Zantac) and famotidine (Pepcid).

Prokinetics: These medications help to stimulate the muscles in the GI tract and can be used to treat conditions such as acid reflux and constipation. Examples include metoclopramide (Reglan) and cisapride (Propulsid).

Antidiarrheals: These medications can be used to treat diarrhea by slowing down the movement of the intestines. Examples include loperamide (Imodium) and bismuth subsalicylate (Pepto-Bismol).

Antispasmodics: These medications can be used to relax the muscles in the GI tract and relieve cramping and spasms. Examples include hyoscyamine (Anaspaz) and dicyclomine (Bentyl).

For hepatobiliary disorders, medications may be used to treat specific conditions or to manage symptoms. For example, medications may be used to treat viral hepatitis, such as interferon and ribavirin, or to manage the symptoms of cirrhosis, such as diuretics and lactulose.

It is important to work with a healthcare provider to determine the most appropriate treatment plan for a specific GI or hepatobiliary disorder. The choice of medication and dosage will depend on the specific condition being treated and the individual patient’s needs.

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