Posted: November 29th, 2022

Sally is a 50-year-old female a jogger

Part 1: Advanced Pharmacology

Sally is a 50-year-old female who has been a jogger for several years. She has recently been diagnosed with osteoarthritis. She has been taking ibuprofen for 3 months but states that “it does not help” and hurts her stomach. The health care provider prescribes celecoxib (Celebrex) 100 mg orally twice a day.

1. Describe the first-line therapy for osteoarthritis and (One paragraph)

a. Explain the mechanism of action (One paragraph)

Sally expresses concern about all the recent news about heart problems and celecoxib (Celebrex).

2. What information should be included in a teaching plan to help her understand about taking celecoxib and the benefits and risks? (Two paragraphs)

Ibuprofen and celecoxib are both nonsteroidal anti-inflammatory drugs.

3. Explain how they are similar and different (Two paragraphs)

The number of words in each paragraph should be similar

Part 2: Advanced Pharmacology (48 hours)

Topic: Pharmacology effects of HIV drug during pregnancy.

Disease state: HIV during pregnancy

1. Introduce the topic (One paragraph)

a. Static data at the global level

b. Static data the USA

2. Describe the HIV during pregnancy (One paragraph)

3. Describe the pathophysiology of the disease state. (One paragraph)

4. Describe the three main pharmacological agents used for treatment and their effects

a. EFV (One paragraph)

b. lamivudine (3TC) (One paragraph)

c. tenofovir disoproxil fumarate (TDF) (One paragraph)

5. Describe the effects e expected of the three pharmacological agents used for treatment and their effects

a. EFV (One paragraph)

b. lamivudine (3TC) (One paragraph)

c. tenofovir disoproxil fumarate (TDF) (One paragraph)

6. Describe the side effects e expected of the three pharmacological agents used for treatment and their effects

a. EFV (One paragraph)

b. lamivudine (3TC) (One paragraph)

c. tenofovir disoproxil fumarate (TDF) (One paragraph)

7. Describe the treatment education related to advanced practice nurse.

a. EFV (One paragraph)

b. lamivudine (3TC) (One paragraph)

c. tenofovir disoproxil fumarate (TDF) (One paragraph)

The number of words in each paragraph should be similar

Part 3: Theoretical and nursing

Topic: Theory Development and Assessment

1. Explain the science and art of theory development and Assessment (Six paragraphs)

The number of words in each paragraph should be similar

Part 4: Theoretical and nursing (48 hours)

Topic: Critical Research Appraisal Assignment

Goal: You will critically appraise a research design

1. Briefly, describe the characteristics of qualitative research and

a. Identify nursing issues/phenomena that lend themselves to a qualitative research approach.

2. Compare and contrast three different qualitative research methodologies.

a. Grounded theory

b. Phenomenological

c. Ethnography

3. Briefly, discuss the strengths and weaknesses of qualitative research evidence for informing nursing practice.

a. Communicate how this research design used in research.

4. According to Qualitative research explain:

a. Identify the purpose of the study.

b. Design of the study

i. Explain why you think it is either appropriate or inappropriate to meet the purpose.

5. dentify ethical issues related to the study and how they were/were not addressed and

a. Identify the sampling method

i. Recruitment strategy that was used.

ii. Discuss whether sampling and recruitment were appropriate to the aims of the research.

6. Identify the data collection method(s) and

a. Discuss whether the method(s) is/are appropriate to the aims of the study.

b. Identify how the data was analyzed

i. Discuss whether the method(s) of analysis is/are appropriate to the aims of the study.

7. Identify four (4) criteria by which the rigor of a qualitative project can be judged.

a. Discuss the rigor of this study using the four criteria.

b. Describe the findings of the study

c.Identify any limitations.

8. Discuss the trustworthiness and applicability of the study.

a. Include in your discussion any implications for the discipline of nursing.

9. Describe the characteristics of quantitative research.

a. Identify nursing issues/phenomena that lend themselves to a quantitative research approach

10. Differentiate between observational and interventional research designs

a. Also between experimental and quasi-experimental designs.

b.Outline the difference between inferential and descriptive statistics and their relationship to levels of measurement.

c. Communicate how this research design used in research.

11. According to Qualitative research explain:

a. Identify the purpose and design of the study.

b. Explain what is meant by ‘blinding’ and ‘randomization’ and discuss c. how these were addressed in the design of the study.

d. Identify ethical issues related to the study and how they were/were not addressed.

12. Explain the sampling method and

a. Recruitment strategy that was used.

b. Discuss how the sample size was determined

c. Outline how the data was collected and identify any data collection instrument(s).

13. Define the terms validity and reliability and

a. Discuss how the validity & reliability of the instruments were/were not addressed in this study and why this is important.

b. Outline how the data were analyzed.

14. Identify the statistics used and the level of measurement of the data described by each statistical test – include in your discussion an explanation of terms used.

a. Briefly, outline the findings and identify any limitations of the study

15. Discuss the trustworthiness and applicability of the study.

a. Include in your discussion an explanation of the term statistical significance and name the tests of statistical significance used in this study.

Part 5: Capstone

PICOT question: Is it possible that the rate of errors due to incompatibility of intravenous medications is reduced by implementing a training program for nurses for 8 weeks, compared to the rate of errors before training? Is it possible to reduce the rate of errors due to incompatibility of intravenous medications by implementing an 8-week training program for nurses, compared to the rate of errors prior to training?

1. Which measurement tools are available for Assessment of your research? (Three paragraphs)

Part 6: Capstone

PICOT question: Can the implementation of a 2-month program on sexually transmitted diseases in adolescents aged 14 to 17 years improve their knowledge about the prevention of sexually transmitted diseases compared to their knowledge before the program’s implementation?

1. Which measurement tools are available for Assessment of your research? (Three paragraphs)

Part 7: Capstone

Picot question: Is it possible that the turnover rate due to burnout is reduced after implementing a mental health program for 10 weeks, compared to the nurses’ turnover rate before the program?

1. Which measurement tools are available for Assessment of your research? (Three paragraphs)

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