Posted: September 21st, 2022

NUR 641E Topic 6: Gastrointestinal And Genitourinary Systems:

NUR 641E Topic 6: Gastrointestinal And Genitourinary Programs: Chosen Pathophysiology And Pharmacologic Remedy
NUR 641E Topic 6: Gastrointestinal And Genitourinary Programs: Chosen Pathophysiology And Pharmacologic Remedy

Apr 7-13, 2022

Max Factors:206

Targets:

Describe regular pathophysiology and alterations of the gastrointestinal and genitourinary programs.
Combine data of pathophysiology and pharmacology into instructing and academic supplies in various settings.
Describe a pharmacological intervention utilizing an evidence-based therapy guideline.
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Topic 6 DQ 1
Apr 7-9, 2022

Select a medical situation from the gastrointestinal or genitourinary programs and clarify the pathophysiology modifications that will happen. What affected person training would should be included associated to this dysfunction? Just be sure you choose a special medical situation than your friends. Embody the identify of the medical situation within the topic line in order that the medical situation could be adopted. Embody your references in APA model.

REPLY TO DISCUSSION

VB

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Replies to Vanessa Brown

Diverticulitis

The situation often called diverticulitis is an an infection or irritation of the diverticula, that are most regularly situated within the decrease part of the big gut (Mayo Clinic, n.d.). Diverticula are tiny pouches that may develop in elements of the digestive tract’s fragile lining, most regularly within the colon (Mayo Clinic, n.d.). When a diverticula tears, an an infection or irritation outcomes, inflicting excessive abdomen discomfort, nausea, vomiting, fever, and modifications in bowel patterns (Mayo Clinic, n.d.).The therapies can embrace bowel relaxation, way of life modifications (together with weight loss program), and antibiotics. In some excessive and/or recurring instances of diverticulitis, surgical procedure is important. A few of the danger elements for growing diverticulitis are age, lack of train, weight problems, smoking, weight loss program excessive in fats and low in fiber, and sure medicines (NSAIDs, steroids, opioids).

References

Mayo Clinic. (n.d.). Diverticulitis. Mayoclinic.org. https://www.mayoclinic.org/diseases-conditions/diverticulitis/symptoms-causes/syc-20371758

REPLY

LH
Topic 6 DQ 2
Apr 7-11, 2022

Choose a medicine utilized in evidence-based therapy pointers for the situation chosen within the first dialogue Question Assignment. Share the mechanism of motion of this treatment and hints for monitoring, unwanted effects, and drug interactions of which one ought to be conscious. Just be sure you choose a special treatment than your friends. Embody the identify of the treatment within the topic line in order that the medicines could be adopted. Embody your references in APA model.

REPLY TO DISCUSSION

VB

Metronidazole

Metronidazole (Flagyl) is part of the antibiotic therapy that can be utilized with treating diverticulitis. It may be given orally or intravenously for this objective. The mechanism of motion of metronidazole is that it “diffuses into the organism, inhibits protein synthesis by interacting with DNA and inflicting a lack of helical DNA construction and strand breakage. Due to this fact, it causes cell dying in prone organisms” (Weir & Le, 2021). Whereas a affected person is taking this treatment for an prolonged time frame, labs akin to a CBC w/differential ought to be monitored for modifications (particularly aged or these with renal/hepatic points), observe for brand spanking new onset of neurological signs, extreme or bloody diarrhea (doable C. Diff an infection), and monitor for different doable hostile results (Weir & Le, 2021). Some unwanted effects that will happen are nausea, vomiting, metallic style within the mouth, dry mouth, diarrhea, or headache. Some drug interactions that should be mentioned are the usage of alcohol or alcohol containing medicines, lithium, glucocorticoids, and warfarin. The alcohol will trigger a severe disulfiram-like response, lithium excretion by the kidneys could be compromised, oxidative metabolism of the metronidazole is brought on by the glucocorticoids, and the metabolism of warfarin is inhibited with metronidazole (Weir & Le, 2021).

References

Weir, C., & Le, J. (2021). Metronidazole. NCBI. https://www.ncbi.nlm.nih.gov/books/NBK539728/

NUR 641E Topic 6: Gastrointestinal And Genitourinary Programs: Chosen Pathophysiology And Pharmacologic Remedy — Topic 6 CLC – Employees Coaching

Factors

Assessment Traits

Group

Requires Lopeswrite

Assessment Description

It is a Collaborative Studying Neighborhood (CLC) task.

This task requires completion of two elements: a presentation and an academic useful resource.

Half 1: Presentation

Create a PowerPoint presentation (15-20 slides, with speaker notes) for a workers coaching assembly on the pathophysiology and pharmacologic brokers for a choose illness course of.

Every CLC will select one illness course of from the next record and acquire teacher approval to keep away from duplication:

Alzheimer’s Illness
Bronchial asthma
Diabetes Kind 2
Epilepsy
Gastroesophageal Reflux Illness (GERD)
Hypertension
Hypothyroidism
A number of Sclerosis
Peptic Ulcer Illness
Tuberculosis
Describe the physiology and pathophysiology of the illness, medical manifestations, and analysis (e.g., labs, imaging).

Describe the pharmacologic therapy of the illness, together with pharmacokinetics, pharmacodynamics, drug interactions, unwanted effects, hostile reactions, and utility of the nursing course of in monitoring the drug remedy.

Half 2: Academic Useful resource

Utilizing your chosen illness course of from Half 1, develop an academic useful resource that may help workers in growing affected person data of medicines and drugs compliance.

The automobile to your instructional useful resource might embrace pamphlets, handouts, or every other temporary, concise medium to convey the data to workers.

Common Necessities

Discuss with the useful resource, “Creating Efficient PowerPoint Displays,” situated within the Scholar Success Heart, for added steerage on finishing this task within the acceptable model.

Whereas APA model is just not required for the physique of this task, stable tutorial writing is predicted, and documentation of sources ought to be offered utilizing APA formatting pointers, which could be discovered within the APA Type Information, situated within the Scholar Success Heart.

This task makes use of a rubric. Please Assessment the rubric previous to starting the task to turn out to be accustomed to the expectations for profitable completion.

You might be required to submit this task to LopesWrite. A hyperlink to the LopesWrite technical help articles is situated in Class Sources when you want help.

Topic 7 DQ 1
Apr 14-16, 2022

Select a medical situation from the neurological, musculoskeletal, or integumentary system and clarify the pathophysiology modifications that will happen. What affected person training would should be included associated to this dysfunction? Just be sure you choose a special medical situation than your friends. Embody the identify of the medical situation within the topic line in order that the medical situation could be adopted. Embody your references in APA model. NUR 641E Topic 6: Gastrointestinal And Genitourinary Programs: Chosen Pathophysiology And Pharmacologic Remedy

REPLY TO DISCUSSION

NS

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Alopecia Areata

Alopecia areata is an autoimmune situation the place the physique assaults its hair follicles, inflicting hair loss anyplace on the physique. The hair loss sometimes happens in round patches that will overlap. You will need to educate the affected person on the basis reason behind their analysis and their therapy choices obtainable to them. It’s also essential to coach correct weight loss program of zero.Eight grams of protein per kilogram of physique weight and discontinuing medicines that will have an effect on hair development. You too can supply help and counseling to Help with dealing with hair loss. Suggesting numerous styling strategies and hair colours can even Help in lowering the looks of thinning hair quantity and help with coping.

References

Hair loss sorts: Alopecia areata overview. American Academy of Dermatology. (2022). Retrieved April 18, 2022, from https://www.aad.org/public/ailments/hair-loss/sorts/alopecia

Mims. (n.d.). Alopecia affected person training. MIMS Malaysia. Retrieved April 18, 2022, from

Minoxidil, or extra generally often called Rogaine, is a well-known therapy for alopecia areata. Minoxidil helps enhance blood provide and vitamins to the hair follicles, serving to to strengthen present hair follicles and selling hair development. Some frequent unwanted effects of minoxidil are irritation, eczema, irregular hair development on the physique, redness at utility web site, burning, worsening hair loss. It’s cautioned that one minoxidil is used, it ought to be used indefinitely, with obvious hair development inside a minimal of 4 months; keep away from contact with scalp as soon as it’s utilized as it will possibly simply be rubbed off; might expertise change in hair colour; keep away from in sufferers with coronary heart points; keep away from contact with eyes.

Reference

Goren, A., Naccarato, T., Situm, M., Kovacevic, M., Lotti, T., & McCoy, J. (2017). Mechanism of motion of minoxidil within the therapy of androgenetic alopecia is probably going mediated by mitochondrial adenosine triphosphate synthase-induced stem cell differentiation. Journal of organic regulators and homeostatic brokers, 31(four), 1049–1053.

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Mechanism of Motion

Levodopa is transformed to dopamine in each the CNS and the periphery. Inhibitors of dopamine decarboxylase forestall Levodopa from being transformed to dopamine within the periphery, permitting extra Levodopa to penetrate the Blood-Mind Barrier (Gandhi KR, 2021). As soon as transformed to dopamine, it acts on postsynaptic dopaminergic receptors, compensating for the lack of endogenous dopamine.

Hints for monitoring

People utilizing Levodopa should frequently monitor their BUN, creatinine, and hepatic perform (Gandhi KR, 2021). A wholesome liver is essential for folks on Levodopa since it’s the web site of decarboxylation. When an individual has glaucoma, it’s also important to test their intraocular stress to make sure it’s protected. Earlier than and whereas taking Levodopa, it’s also very important to test for peripheral neuropathy to see if it would worsen. Sufferers also needs to have their dyskinesia checked frequently. Due to this fact, it’s essential to look at sufferers who take dopaminergic medicines for psychotic conduct and hallucinations. Hallucinations can occur when persons are confused or have many goals. NUR 641E Topic 6: Gastrointestinal And Genitourinary Programs: Chosen Pathophysiology And Pharmacologic Remedy

Unintended effects

Taking Levodopa’s commonest unwanted effects are nausea, dizziness, headache, and sleepiness. Typical unwanted effects for older individuals who take Levodopa are confusion, hallucinations, delusions, psychosis, and agitation.

Drug interactions

Levodopa is contraindicated when monoamine oxidase inhibitors (MAOIs) are used concurrently, as this would possibly lead to a hypertensive disaster (Gandhi KR, 2021). Nonetheless, when transitioning from Levodopa to an MAOI or vice versa, a 14-day washout interval ought to be noticed. Sufferers utilizing D2 antagonists might lower the consequences of Levodopa, which can reduce the drug’s constructive advantages (Gandhi KR, 2021).

Reference:

Gandhi KR, S. A. (2021, April 30). Levodopa (L-dopa) – StatPearls – NCBI bookshelf. Nationwide Heart for Biotechnology Data. https://www.ncbi.nlm.nih.gov/books/NBK482140/

Topic Eight DQ 1
Apr 21-23, 2022

Select a medical situation from the endocrine system and clarify the pathophysiology modifications that will happen. What affected person training would should be included associated to this dysfunction? Just be sure you choose a special medical situation than your friends. Embody the identify of the medical situation within the topic line in order that the medical situation could be adopted. Embody your references in APA model.

REPLY TO DISCUSSION

Learn

GOITER

Goiter is an irregular development of the thyroid gland situated on the base of the neck. This will current as an enlargement of the thyroid or irregular cell development that will trigger lumps or nodules within the thyroid. Goiter could also be a results of change in thyroid hormones or no change in any respect. Some frequent causes of goiter is lack of iodine consumption from an inidivuduals weight loss program. Relying on the reason for goiter, a person might exhibit signs of hyperthyroidsim or hyperthyroidism. In obstructive goiter, indicators and signs embrace difficulties swallowing, labored respiratory, hoarseness, cough, and loud night breathing. Therapy of goiter varies on the trigger, treating the signs and problems. You will need to educate sufferers with goiter on the reason for their goiter; sufficient iodine consumption; annual bodily exams and neck exams; annual blood work. For sufferers on medical therapy for goiter, it is very important reinforce the significance of taking prescribed medicines as ordered.

Reference

Can AS, Rehman A. Goiter. [Updated 2021 Aug 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Out there from: https://www.ncbi.nlm.nih.gov/books/NBK562161/

Topic Eight DQ 2
Apr 21-25, 2022

Choose a medicine utilized in evidence-based therapy pointers for the situation chosen within the first dialogue Question Assignment. Share the mechanism of motion of this treatment and hints for monitoring, unwanted effects, and drug interactions of which one ought to be conscious. Just be sure you choose a special treatment than your friends. Embody the identify of the treatment within the topic line in order that the medicines could be adopted. Embody your references in APA model.

REPLY TO DISCUSSION

Posted Date

Propylthiouracil (PTU)

Propylthiouracil is used to deal with hyperthyroidism (irregular thyroid exercise), Graves’ illness, and poisonous goiter (enlarged thyroid). It’s also often used to alleviate signs previous to thyroid surgical procedure or radioactive iodine remedy.

Mechanism of motion

Propylthiouracil suppresses thyroid hormone synthesis. It really works by blocking thyroid peroxidase, which usually converts iodide to iodine and integrates it into tyrosine (Amisha & Rehman, 2021). The first parts of thyroxine (T4) and triiodothyronine (T3) will not be fashioned (T3). It inhibits T4 to T3 conversion peripherally. It impacts thyroid hormones within the thyroid gland or within the blood.

Hints of monitoring

Thyroid perform assessments ought to be monitored whereas on PTU therapy. Sufferers utilizing warfarin should even have their prothrombin time monitored. PTU therapy contains affected person training and counseling. The affected person ought to be suggested: Notify your physician when you turn out to be pregnant or plan to turn out to be pregnant whereas taking the medication. Report any fever, drug eruptions, or an infection to your physician. Notify your physician when you have nausea, proper higher quadrant discomfort, or jaundice. Agranulocytosis signs embrace sore throat, fever, chills, gum or pores and skin infections (Amisha & Rehman, 2021). Extreme hypotension is one other symptom.

Unintended effects

Signs of an allergic response (hives, problem respiratory, swelling of the face or throat) (fever, sore throat, burning eyes, pores and skin ache, crimson or purple pores and skin rash with blistering and peeling). Propylthiouracil harms the liver (particularly through the first 6 months of therapy). Should you undergo nausea, vomiting, higher abdomen discomfort, itching, fever, fatigue, lack of urge for food, darkish urine, clay-colored feces, or jaundice, cease taking propylthiouracil and notify your physician (yellowing of the pores and skin or eyes).

Drug Interactions

Digoxin (digitalis); theophylline; coronary heart or blood stress drugs; or a blood thinner—warfarin, Coumadin, Jantoven—all have drug interactions with Propylthiouracil.

References

Amisha, F., & Rehman, A. (2021, July 11). Propylthiouracil (PTU) – StatPearls – NCBI bookshelf. Nationwide Heart for Biotechnology Data. https://www.ncbi.nlm.nih.gov/books/NBK549828/

Cerner Multum. (2021, June 11). Propylthiouracil. Medication.com. https://www.medicine.com/mtm/propylthiouracil.html

Topic 2 Content material Lesson Presentation
REVIEW ASSIGNMENT

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167

Rubric

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Standing

Revealed

Assessment Description

Create an Eight-9 slide presentation with speaker notes a couple of chosen illness course of and drug class. The presentation ought to present content material particular data on the chosen illness course of and drug class for employees or learners in a medical setting.

Comply with these steps:

Choose a illness course of and a drug class used to deal with the illness course of.
Describe pharmacokinetics and pharmacodynamics of the drug associated to the pathophysiology of the illness course of.
Describe the product, its meant use, unwanted effects, hostile reactions, and questions of safety.
Determine ethnic, cultural, and genetic variations in sufferers that will have an effect on the security or efficacy of medicines.
How would you monitor the specified impact is achieved?
Remember to embrace three to 5 references.

Whereas APA model is just not required for the physique of this task, stable tutorial writing is predicted, and documentation of sources ought to be offered utilizing APA formatting pointers, which could be discovered within the APA Type Information, situated within the Scholar Success Heart.

This task makes use of a rubric. Please Assessment the rubric previous to starting the task to turn out to be accustomed to the expectations for profitable completion.

You aren’t required to submit this task to LopesWrite.

Content material Lesson Presentation – Rubric

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Illness Course of and Drug Class

25.05 factors

Standards Description

Illness Course of and Drug Class

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