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Posted: August 31st, 2022
Assignment: Impact of Drug Interactions and Adverse Events on Therapeutic
Impact of Drug Interactions and Adverse Events on Therapeutic
In your preliminary put up, please reply the next questions associated to the affect of drug interactions and opposed occasions on therapeutic. Make sure you use three evidence-based assets to incorporate scientific follow tips.
Impact of Drug Interactions and Adverse Events on Therapeutic
A 60-year-old White lady with newly recognized peptic ulcer illness, generalized nervousness dysfunction, and iron deficiency anemia. She additionally has a protracted historical past of bronchial asthma and melancholy. She is a robust believer of natural drugs. She takes St. John’s wort for her melancholy, iron drugs for her anemia, and alprazolam (Xanax) as wanted for her nervousness. Throughout her bronchial asthma exacerbation, she is instructed to take prednisone for no less than 5 days. She additionally takes esomeprazole (Nexium) for her peptic ulcer illness. Three months later, she skilled extreme fatigue, shortness of breath, dizziness, and swelling/soreness within the tongue. Her bronchial asthma is nicely managed with the occasional use of albuterol (Proventil) inhaler. Throughout her bodily examination, her doctor suspected that she had bacterial vaginosis and gave her a prescription for a 1-week course of metronidazole (Flagyl). She drinks no less than two to a few cans of beer per day.
Analysis: Drug–Drug Interactions
1. St. John’s wort is understood to inhibit which of her treatment that’s identified to be metabolized by cytochrome P-450 (CYP3A4) and may doubtlessly trigger her to expertise important fatigue?
2. Which of her treatment may intervene with the absorption of her iron drugs?
three. Which of her treatment may doubtlessly trigger her to develop vitamin B12 deficiency?
four. How does metronidazole intervene with alcohol?
5. If she was given a prescription for ketoconazole, which of her treatment may intervene with its absorption?
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