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Posted: August 13th, 2022
Assignment 3: Classes of agents that can damage DNA
Assignment three: Classes of agents that can damage DNA
What are the 2 principal lessons of agents that can damage DNA, which doesn’t lead to harmful merchandise instantly, however relatively the merchandise are metabolized by cells into varieties that are dangerous? (1 level)
Describe how deamination happens, present an instance of a spontaneous deamination and what the result’s. (four factors)
Describe intimately how direct restore of DNA works. (three factors)
What typically makes a primary technology most cancers drug much less fascinating than a second technology one? (2 level)
Discover an instance of a second technology most cancers drug that interacts with DNA within the e-journals and talk about the journal article (10 factors)
Utilizing any info you can get hold of from applicable e-journals, high quality Web websites or different applicable sources, discover a illness the place antisense analysis has already been finished. You will have to discover a illness state the place an antisense molecule has been designed to focus on the mRNA of a protein within the illness. Please present the next info, being certain to reference your work: (1-7) Discover a illness the place antisense analysis has already been finished utilizing any info you can get from good e-journals, good Web websites, or different good sources. You will have to discover a illness state the place an antisense molecule has been made to focus on the mRNA of a protein within the illness. Please give the next particulars and ensure to quote your work: (1-7
The illness you selected to focus on [2pts]
The position of the protein focused by the antisense [3pts]
The particular sequence of the mRNA focused [3pts]
The particular sequence of your antisense molecule [3pts]
The particular amino acid sequence affected by binding of the antisense molecule [3pts]
Why you focused that particular sequence [3pts]
Modifications made to the antisense molecule to reinforce its resistance to RNAse H; if no modifications have been finished in your molecule, please talk about doable modifications that can be finished. [3pts].
Necessities: Detailed, in personal phrases and supply references
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