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Posted: August 4th, 2022
Pharmacokinetics And Pharmacodynamics
Pharmacokinetics describes what the body does to the drug through absorption, distribution, metabolism, and
excretion, whereas pharmacodynamics describes what the drug does to the body.
Photo Credit: Getty Images/Ingram Publishing
When selecting drugs and determining dosages for patients, it is essential to consider individual patient factors
that might impact the patient’s pharmacokinetic and pharmacodynamic processes. These patient factors include
genetics, gender, ethnicity, age, behavior (i.e., diet, nutrition, smoking, alcohol, illicit drug abuse), and/or
pathophysiological changes due to disease.
For this Assignment help – Discussion, you reflect on a case from your past clinical experiences and consider how a patient’s
pharmacokinetic and pharmacodynamic processes may alter his or her response to a drug.
To Prepare
Review the Resources for this module and consider the principles of pharmacokinetics and
pharmacodynamics.
Reflect on your experiences, observations, and/or clinical practices from the last 5 years and think about
how pharmacokinetic and pharmacodynamic factors altered his or her anticipated response to a drug.
Consider factors that might have influenced the patient’s pharmacokinetic and pharmacodynamic
processes, such as genetics (including pharmacogenetics), gender, ethnicity, age, behavior, and/or possible
pathophysiological changes due to disease.
Think about a personalized plan of care based on these influencing factors and patient history in your case
study.
By Day 3 of Week 1
Post a description of the patient case from your experiences, observations, and/or clinical practice from the last 5
years. Then, describe factors that might have influenced pharmacokinetic and pharmacodynamic processes of
the patient you identified. Finally, explain details of the personalized plan of care that you would develop based
on influencing factors and patient history in your case. Be specific and provide examples.
Four references not more than 5years
Rosenthal, L. D., & Burchum, J. R. (2018). Lehne’s pharmacotherapeutics for advanced practice providers. St.
Louis, MO: Elsevier.
Chapter 1, “Prescriptive Authority” (pp. 1–3)
Chapter 2, “Rational Drug Selection and Prescription Writing” (pp. 5–9)
Chapter 3, “Promoting Positive Outcomes of Drug Therapy” (pp. 11–16)
Chapter 4, “Pharmacokinetics, Pharmacodynamics, and Drug Interactions” (pp. 17–40)
Chapter 5, “Adverse Drug Reactions and Medical Errors” (pp. 41–49)
Chapter 6, “Individual Variation in Drug Response” (pp. 51–56)
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