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Posted: June 30th, 2022
Impact of Drug Interactions and Adverse Events on Therapeutic
Impact of Drug Interactions and Adverse Events on Therapeutic
In your preliminary put up, please reply the next questions associated to the influence of drug interactions and hostile occasions on therapeutic. Make sure you use three evidence-based assets together with medical observe tips.
Impact of Drug Interactions and Adverse Events on Therapeutic
A 60-year-old White girl with newly identified peptic ulcer illness, generalized nervousness dysfunction, and iron deficiency anemia. She additionally has a protracted historical past of bronchial asthma and despair. She is a robust believer of natural drugs. She takes St. John’s wort for her despair, iron drugs for her anemia, and alprazolam (Xanax) as wanted for her nervousness. Throughout her bronchial asthma exacerbation, she is instructed to take prednisone for not less than 5 days. She additionally takes esomeprazole (Nexium) for her peptic ulcer illness. Three months later, she skilled extreme fatigue, shortness of breath, dizziness, and swelling/soreness within the tongue. Her bronchial asthma is properly managed with the occasional use of an albuterol (Proventil) inhaler. Throughout her bodily examination, her doctor suspected that she had bacterial vaginosis and gave her a prescription for a 1-week course of metronidazole (Flagyl). She drinks not less than two to a few cans of beer per day.
Three months later, she was very drained, had bother respiratory, felt dizzy, and her tongue was sore and swollen. Her bronchial asthma is properly beneath management when she makes use of an albuterol (Proventil) inhaler now and again. Throughout her bodily examination, her physician thought she may need bacterial vaginosis and gave her a prescription for metronidazole to take for every week (Flagyl). She drinks two to a few cans of beer a day, not less than.
Analysis: Drug–Drug Interactions
1. St. John’s wort is understood to inhibit which of the remedy is understood to be metabolized by cytochrome P-450 (CYP3A4) and may doubtlessly trigger her to expertise vital fatigue.
2. Which of her remedy may intrude with the absorption of her iron drugs?
three. Which of her remedy may doubtlessly trigger her to develop vitamin B12 deficiency?
four. How does metronidazole intrude with alcohol?
5. If she was given a prescription for ketoconazole, which of her remedy may intrude with its absorption?
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