Posted: June 15th, 2022

Explain how the empirical result that protein structures are composed

Are you able to assist me with this downside set?1. Explain how the empirical result that protein structures are composed of a restricted variety of area construction motifs gives an strategy to fixing the Levinthal Paradox.2. Present a easy calculation explaining how the truth that most amino acid residues inside globular proteins fall inside a-helices or ß-strands units an higher restrict for the variety of area construction motifs that one expects to seek out in the totality of globular protein structures.three. There are two faculties of thought concerning the nature of the main driving pressure for protein folding. One holds that the main pressure is derived from formation of intrachain hydrogen bonds. The opposite holds that it’s the hydrophobic impact that is the dominant driving pressure. Summarize the experimental proof for every place.four. Describe an instance of an enzyme energetic website containing a bunch of amino acid residues that destabilizes the total construction of the enzyme, and clarify why that is so.5. Explain why in research directed towards evaluating the significance of a selected aspect chain for enzyme catalysis, the residue in query is often mutated to an alanine fairly than a glycine.

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