Posted: December 20th, 2021

Alterations in Immunity pathophysiology Nursing

Alterations in Immunity Pathophysiology
The pathophysiology related with the potential disease includes the signs of Afebrile, pulse, respiratory rate, and normal blood pressure. Such health signs show the impact of the health condition on the patient. Donna should be able to recognize the impacts of these health impacts. A skin test determined that Donna became sensitized to potential allergens in cat dander conditions. Her lymphocytes were observed to produce antibodies which ended up in the external surface of the mast cells (Drossman, 2016). Cat dander allergens were linked to the IgE antibodies causing the degranulation of the cells and release of inflammatory mediators. The mediators led to vasodilation that led to the development of redness.
Donna suffering from allergic rhinitis, immediate (type 1) hypersensitivity is the type of hypersensitivity reaction facing Donna. The reaction was caused by the inhalants including dust, mold, and pollen. The process of vasodilation is the potential disease process that could have occurred to the patient based on the patient’s medical history (Lee & Park, 2014). In understanding the medical and family history of Donna, some of the assessment questions that would be asked include what is the personal history of Donna’s allergies? History of asthma? Any families history of allergies? Any potential hay fever? Any history of respiratory problems? and Any signs of asthma being present in the near future.
There are critical signs indicating that Donna is not suffering from acute severe infections including the vital signs being within the normal limits. The normal limit shows that Donna is not suffering from acute severe infections (Rabinovitch, Guignabert, Humbert & Nicolls, 2014). The disease process led to vasodilation and increased level of permeability because of inflammatory mediators released through the mast cells due to increased secretion. The evidence recorded is also not adequate and appropriate. It only occurs the postnasal drainage which is not adequate.

References
Drossman, D. A. (2016). Functional gastrointestinal disorders: history, pathophysiology, clinical features, and Rome IV. Gastroenterology, 150(6), 1262-1279.
Lee, Y. J., & Park, K. S. (2014). Irritable bowel syndrome: emerging paradigm in pathophysiology. World Journal of Gastroenterology: WJG, 20(10), 2456.
Rabinovitch, M., Guignabert, C., Humbert, M., & Nicolls, M. R. (2014). Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension. Circulation Research, 115(1), 165-175.

Respond to the question using the lessons and vocabulary found in the readings. Support your answers with examples and research. Your responses should clarify your understanding of the topic. They should be your own, original, and free from plagiarism. Follow APA format for writing style, spelling and grammar, and citation of sources.

Start reviewing and responding to the postings of your classmates as early in the week as possible. Respond to at least two of your classmates. Participate in the discussion by analyzing each response for completeness and accuracy and by suggesting specific additions or clarifications for improving the discussion question response. Complete your participation for this assignment by Wednesday, September 13, 2017.

Alterations in Immunity

Donna, a twenty-one-year-old nursing student, comes to her nurse practitioner in December with a five-week history of itchy eyes and nasal congestion with watery nasal discharge. She also complains of a “ticklingвЂк cough, especially at night, and she has had episodes of repetitive sneezing. She gets frequent “coldsвЂк every spring and fall.

Physical Examination

Vital Signs: Afebrile; respiratory rate, pulse, and blood pressure all normal

Skin: Flaking erythematous rash on the flexor surfaces of both arms

Head, Eyes, Ears, Nose, and Throat: Tender overmaxillary sinuses; sclera red and slightly swollen with frequent tearing; outer nares with red, irritated skin; internal nares with red, boggy, moist mucosa and one medium-sized polyp on each side; pharynx slightly erythematous, with clear postnasal drainage

Lungs: Clear to auscultation and percussion

Answer the questions about Donna and her condition and provide a pathophysiological response in the body. Examine and describe the pathophysiology associated with the possible disease.

What is the possible disease process according to the clientвЂTMs history?
What assessment questions would be useful to ask about her medical and family history?
What evidence suggests that Donna does not have an acute severe infection?
If Donna has allergic rhinitis, what type of hypersensitivity reaction is involved?

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